静脈血栓栓塞預防

加速康復並回歸生活

靜脈血栓栓塞 (VTE) — 包括深層靜脈血栓 (DVT) 和肺栓塞 (PE) — 在美國每 1000 名住院患者中就有 1 人受到影響,並且是導致住院時間延長的的第二大醫療併發症。1,2 美國每年 VTE-相關死亡人數估計為 29.6萬 人,歐洲為 37萬 人。3 

每年用於治療院內初始靜脈血栓栓塞費用高達272億美元(52% 為院內預防費用)和另外 344 億美元用於院內靜脈血栓栓塞復發治療(56% 為院內可預防費用),相關的住院費用給醫療保健系統帶來了沉重的負擔。4 

在美國,每年預估約 1000 名住院患者中就有 1 名發生深層靜脈血栓 (DVT)

美國胸腔科醫師學會® 建議對大出血高風險的急性和危重住院患者進行VTE機械治療。有效的 VTE 治療可顯著降低治療成本、復發風險、發病率和死亡率。5 

深層靜脈血栓 (DVT) 併發症 延遲住院時間 9 天。

20% 至 50% 的初期深層靜脈血栓 (DVT )患者發展為血栓後綜合症候群 (PTS),5% 至 10% 進展為嚴重病例,例如靜脈潰瘍6 ,這使住院時間增加了 9 天,住院費用在現行醫院費用的基礎上增加了 10萬3,860 美元以上。7 

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Reference


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  2. Geerts WH, Bergqvist D, Pineo GF, Heit JA, Samama CM, Lassen MR, Colwell CW. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest. 2008 Jun;133(6 Suppl):381S-453S. doi: 10.1378/chest.08-0656. PMID: 18574271. 
  3. Lin J, Lingohr-Smith M, Kwong WJ. Incremental health care resource utilization and economic burden of venous thromboembolism recurrence from a U.S. payer perspective. J Manag Care Pharm. 2014 Feb;20(2):174-86. doi: 10.18553/jmcp.2014.20.2.174. PMID: 24456319. 
  4. Mahan CE, Borrego ME, Woersching AL, Federici R, Downey R, Tiongson J, Bieniarz MC, Cavanaugh BJ, Spyropoulos AC. Venous thromboembolism: annualised United States models for total, hospital-acquired and preventable costs utilising long-term attack rates. Thromb Haemost. 2012 Aug;108(2):291-302. doi: 10.1160/TH12-03-0162. Epub 2012 Jun 28. PMID: 22739656. 
  5. Guyatt GH, Akl EA, Crowther M, Gutterman DD, Schuünemann HJ; American College of Chest Physicians Antithrombotic Therapy and Prevention of Thrombosis Panel. Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest. 2012 Feb;141(2 Suppl):7S-47S. doi: 10.1378/chest.1412S3. Erratum in: Chest. 2012 Apr;141(4):1129. Dosage error in article text. Erratum in: Chest. 2012 Dec;142(6):1698. Dosage error in article text. PMID: 22315257; PMCID: PMC3278060. 
  6. Kahn SR. The post-thrombotic syndrome. Hematology Am Soc Hematol Educ Program. 2016 Dec 2;2016(1):413-418. doi: 10.1182/asheducation-2016.1.413. PMID: 27913509; PMCID: PMC6142466. 
  7. Trivedi NN, Abola MV, Kim CY, Sivasundaram L, Smith EJ, Ochenjele G. The Incremental Cost of Inpatient Venous Thromboembolism After Hip Fracture Surgery. J Orthop Trauma. 2020 Apr;34(4):169-173. doi: 10.1097/BOT.0000000000001675. PMID: 31977669.